In The Articles

Long Term Urinary Sequelae Following 125 Iodine Prostate Brachytherapy In the early view version of The Journal of Urology, Dr. Crook and colleagues present a single practitioner series of 125I prostate brachytherapy with analysis of long-term sequelae. Patients with low-risk prostate cancer (CaP) were initially assessed with an I-PSS questionnaire and given a short course of androgen deprivation therapy for prostates larger than 50cc. Treatment consisted of implantation of 125I seeds by the Seattle technique. Urinary function was evaluated over the long-term using the I-PSS questionnaire. The study cohort included 484 men treated between 1999 and 2005. Clinical stage was T1 in 65% and T2a in 35%. Median pretreatment PSA was 5.4ngml and median followup was 41 months. No urinary sequelae were recorded after one year in 73% of men. The 3 and 5-year Kaplan-Meier sequelae-free rates were 73%and 69%, respectively. An increase of more than 5 points in the I-PSS or a score greater than 15 was found in 23%. Most of these men had resolution with medical management at a median time of 3 months. For 30%, the symptom flare lasted more than 6 months. Age was the only variable that predicted for prolonged voiding symptoms. Urinary urgency was noted in 6.4% of patients and half of these required anticholinergic medications. Only 4 patients (0.8%) had long term symptoms of urgency. Thirteen men (2.7%) required a catheter later than 1 year after treatment and 2 of these required a transurethral resection of the prostate. Urethral stricture occurred in 8 men (1.7%), 3 of whom had required catheterization. The authors point out that the 27% long term urinary sequelae noted in this series is a single practitioner, single institution result that may not apply to the community in general. Long Term Urinary Sequelae Following 125 Iodine Prostate Brachytherapy

In The News

Health sessions for St. Paul - SUN Weekend Health sessions for St. PaulSUN Weekend, Antigua and Barbuda - Feb 1, 2008A Prostate Cancer Screening organised for today is expected to jump start the list of events scheduled for this month. The screening will be held at the ...

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Jefferson Lab imager can detect beginnings of breast tumors - Daily Press Jefferson Lab imager can detect beginnings of breast tumorsDaily Press, VA - Feb 2, 2008Majewski said there's also interest in using the technology for prostate cancer detection. The scientist said it remains exciting to apply his knowledge of ...

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DAYTRIP: Almost human — exhibit showcases inner workings of robots - Waterbury Republican American DAYTRIP: Almost human — exhibit showcases inner workings of robotsWaterbury Republican American, CT - Feb 1, 2008The da Vinci robot is used for gastric bypass, prostate, heart and general surgery. According to the Robotics Institute of America, 175000 robots are now at ...